几种植物物种中存在单链核糖体失活蛋白样活性。
Presence of single-chain ribosome-inactivating protein-like activities in several plant species.
作者信息
Girbés T, Citores L, Prieto M T, Ferreras J M, Muñoz R, Fernández J M
机构信息
Departamento de Bioquímica, Biología Molecular y Fisiología, Facultad de Ciencias, Universidad de Valladolid, Spain.
出版信息
Cell Mol Biol (Noisy-le-grand). 1992 Nov;38(7):803-12.
The present screening work was devoted to the search for new ribosome-inactivating proteins (RIPs) in 21 plant species. Eight plants proved to be very active, inhibiting protein synthesis in eukaryotic in vitro systems (rat liver, Vicia sativa and wheat germ). They fulfil the major requirements for consideration as type 1 RIPs. Also, eight plants were found to contain haemagglutinating activity of human red cells but this was not related to the simultaneous presence of RIPs.
目前的筛选工作致力于在21种植物中寻找新的核糖体失活蛋白（RIPs）。结果证明，有8种植物具有很强的活性，能够抑制真核体外系统（大鼠肝脏、蚕豆和小麦胚芽）中的蛋白质合成。它们符合被视为1型RIPs的主要要求。此外，还发现有8种植物具有人红细胞凝集活性，但这与同时存在RIPs并无关联。
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