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神经皮肤黑素沉着症患者的液体衰减反转恢复序列磁共振成像上的弥漫性软脑膜高信号。

Diffuse leptomeningeal hyperintensity on fluid-attenuated inversion recovery MR images in neurocutaneous melanosis.

作者信息

Hayashi Masato, Maeda Masayuki, Maji Tomoaki, Matsubara Toshio, Tsukahara Hirokazu, Takeda Kan

机构信息

Department of Radiology, Mie University School of Medicine, Tsu, Mie, Japan.

出版信息

AJNR Am J Neuroradiol. 2004 Jan;25(1):138-41.

Abstract

Neurocutaneous melanosis (NCM) is a rare neuroectodermal dysplasia characterized by large or multiple cutaneous congenital pigmented nevi and benign or malignant melanocytic tumors of the leptomeninges. Although the MR manifestations of this disease have been reported in a small series of cases, the usefulness of fluid-attenuated inversion recovery (FLAIR) MR findings has not been documented. We present a case of NCM that showed diffuse leptomeningeal hyperintensity on FLAIR images. This FLAIR finding may be a clue to the detection of leptomeningeal abnormalities in NCM.

摘要

神经皮肤黑素沉着症(NCM)是一种罕见的神经外胚层发育异常疾病,其特征为存在巨大或多发的皮肤先天性色素痣以及软脑膜的良性或恶性黑素细胞肿瘤。尽管已有少量病例报道了该疾病的磁共振(MR)表现,但液体衰减反转恢复(FLAIR)序列MR表现的应用价值尚未见文献记载。我们报告一例NCM病例,其FLAIR图像显示软脑膜弥漫性高信号。这一FLAIR表现可能是检测NCM中软脑膜异常的线索。

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