血管性头痛患者的心血管反射

Cardiovascular reflexes in patients with vascular headache.

作者信息

Martín R, Ribera C, Moltó J M, Ruiz C, Galiano L, Matías-Guiu J

机构信息

Department of Neurology, Hospital Virgen de los Lirios, Alcoy, University of Alicante, Spain.

出版信息

Cephalalgia. 1992 Dec;12(6):360-4. doi: 10.1111/j.1468-2982.1992.00360.x.

DOI:10.1111/j.1468-2982.1992.00360.x

PMID:1473138

Abstract

We have investigated the autonomic function of 75 patients with migraine by examining cardiovascular reflex function. The results were compared with those of 78 healthy volunteers. Measurements were made between attacks. Patients with migraine showed a smaller heart-rate response to deep breathing but a greater heart-rate response and higher blood pressure to standing when compared to controls. Migraine patients had a higher percentage of established sympathetic lesions (51% vs 17%) and severe (25% vs 5%) or atypical (24% vs 11.5%) global autonomic dysfunction. No significant differences were found among patients with migraine with aura, migraine without aura, and migraine with prolonged aura. Our findings indicate that patients with migraine have sympathetic hypofunction.

摘要

我们通过检查心血管反射功能，对75例偏头痛患者的自主神经功能进行了研究。将结果与78名健康志愿者的结果进行了比较。在发作间期进行测量。与对照组相比，偏头痛患者对深呼吸的心率反应较小，但对站立的心率反应更大且血压更高。偏头痛患者已确诊的交感神经病变百分比更高（51% 对17%），严重（25% 对5%）或非典型（24% 对11.5%）的全身性自主神经功能障碍发生率也更高。有先兆偏头痛患者、无先兆偏头痛患者和伴有长时间先兆偏头痛患者之间未发现显著差异。我们的研究结果表明，偏头痛患者存在交感神经功能减退。