调控细胞凋亡的必需基因。
Essential genes that regulate apoptosis.
作者信息
Osborne B A, Schwartz L M
机构信息
Department of Veterinary Sciences, Program in Molecular and Cellular Biology, University of Massachusetts, Amherst, MA 01003, USA.
出版信息
Trends Cell Biol. 1994 Nov;4(11):394-9. doi: 10.1016/0962-8924(94)90052-3.
PMID:14731815
Abstract
The expression of several genes has been associated with the induction of apoptosis in a wide variety of vertebrate and invertebrate organisms. However, relatively few gene products have been demonstrated to be required for cell death. This review highlights genes that are required for apoptosis and proposes mechanisms by which the proteins encoded by these genes might function.
摘要
在各种各样的脊椎动物和无脊椎动物中，几种基因的表达与细胞凋亡的诱导有关。然而，相对较少的基因产物已被证明是细胞死亡所必需的。这篇综述重点介绍了细胞凋亡所需的基因，并提出了这些基因所编码的蛋白质可能发挥作用的机制。
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