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在三维空间中揭示的联会复合体的中央区域。

The central region of the synaptonemal complex revealed in three dimensions.

作者信息

Schmekel K, Daneholt B

机构信息

Dept of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, S-171 77 Stockholm, Sweden.

出版信息

Trends Cell Biol. 1995 Jun;5(6):239-42. doi: 10.1016/s0962-8924(00)89017-0.

DOI:10.1016/s0962-8924(00)89017-0
PMID:14732128
Abstract

The synaptonemal complex plays a key role in pairing of homologous chromosomes during meiosis. Its gross structure was already known by conventional electron microscopy, but only recently has it been possible to reveal the synaptonemal complex in three dimensions at higher resolution by electron microscope tomography. As the molecular analysis of meiosis is developing rapidly, a more thorough understanding of the principal organization of the synaptonemal complex is essential.

摘要

联会复合体在减数分裂过程中同源染色体配对方面起着关键作用。其总体结构已通过传统电子显微镜为人所知,但直到最近才能够通过电子显微镜断层扫描以更高分辨率揭示联会复合体的三维结构。随着减数分裂分子分析的迅速发展,对联会复合体主要组织结构有更透彻的理解至关重要。

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