Martín Miguel, Llombart-Cussac Antonio, Lluch Ana, Alba Emilio, Munárriz Blanca, Tusquets Ignacio, Barnadas Agustí, Balil Anna, Dorta Javier, Picó César
Servicio de Oncología Médica, Hospital Universitario San Carlos, Madrid, Spain.
Med Clin (Barc). 2004 Jan 17;122(1):12-7. doi: 10.1016/s0025-7753(04)74126-3.
The aim of the El Alamo project was to define the demographic and clinic characteristics, treatment and evolution of women with invasive breast cancer diagnosed in hospitals of the GEICAM group (Spanish Breast Cancer Research Group) between 1990 and 1993.
Data from 4,532 patients were included. Forms were completed according to the medical history of patients, and collected in the GEICAM scientific office, where they were added to a data base.
32 hospitals from 19 provinces and 11 regional communities participated in the study. Mean age of the 4,532 patients was 56.72 years, 1,428 (31.5%) were premenopausal and 2,988 (65.9%) were postmenopausal. Stage II tumors were most frequent (55.5%). Among patients with stage I, II and III at diagnosis, surgery was the first treatment in most (90.7%), radical mastectomy being the most frequent procedure performed (79.7%). 70.4% of 1941 patients with positive axillary node and 37.4% of 1,806 patients without axillary affection received adjuvant chemotherapy with or without hormone therapy.
El Alamo project represents the largest data base on breast cancer in Spain and the results are similar to those observed in other countries such as the USA.
“埃尔阿拉莫”项目的目的是明确1990年至1993年间在GEICAM组（西班牙乳腺癌研究组）各医院诊断出的浸润性乳腺癌女性患者的人口统计学和临床特征、治疗情况及病情发展。
纳入了4532例患者的数据。根据患者病史填写表格，并收集到GEICAM科研办公室，随后录入数据库。
来自19个省和11个自治区的32家医院参与了该研究。4532例患者的平均年龄为56.72岁，其中1428例（31.5%）为绝经前患者，2988例（65.9%）为绝经后患者。II期肿瘤最为常见（55.5%）。在诊断为I期、II期和III期的患者中，大多数（90.7%）的首选治疗方法是手术，其中最常进行的手术是根治性乳房切除术（79.7%）。1941例腋窝淋巴结阳性患者中有70.4%以及1806例无腋窝受累患者中有37.4%接受了辅助化疗，部分患者还接受了激素治疗。
“埃尔阿拉莫”项目是西班牙最大的乳腺癌数据库，其结果与美国等其他国家观察到的结果相似。
