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[重症肌无力的外科治疗及其评估]

[Surgical treatment of myasthenia gravis and its evaluation].

作者信息

Pan T C

机构信息

Tongji Hospital, Tongji Medical University, Wuhan.

出版信息

Zhonghua Wai Ke Za Zhi. 1992 Apr;30(4):234-6, 256.

PMID:1473408
Abstract

30 cases of myasthenia gravis (MG) were treated with thymectomy. Before and after operation, peripheral blood lymphocyte subpopulation was determined in 10 cases and acetylcholine receptor antibody titer was determined in 6. The results confirmed the efficacy of thymectomy in treating MG. We suggest that application of hormone for regulating immune function of the body and/or plasma exchange for alleviating symptoms in patients with generalized MG before and after the operation. The results of treatment did not correlate with age, sex, length, and course of the disease. Radical operation, proper anaesthesia and appropriate antibiotics may ensure a smooth operation and high curative effect.

摘要

30例重症肌无力(MG)患者接受了胸腺切除术。术前和术后,对10例患者测定了外周血淋巴细胞亚群,对6例患者测定了乙酰胆碱受体抗体滴度。结果证实了胸腺切除术治疗MG的疗效。我们建议在手术前后对全身型MG患者应用激素调节机体免疫功能和/或进行血浆置换以缓解症状。治疗结果与年龄、性别、病程长短无关。根治性手术、适当的麻醉和合适的抗生素可确保手术顺利进行并取得高疗效。

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