ROSO：优化用于微阵列的寡核苷酸探针
ROSO: optimizing oligonucleotide probes for microarrays.
作者信息
Reymond Nancie, Charles Hubert, Duret Laurent, Calevro Federica, Beslon Guillaume, Fayard Jean-Michel
机构信息
Biologie Fonctionnelle, Insectes et Interactions (BF2I), UMR INRA/INSA de Lyon, 69621 Villeurbanne, France.
出版信息
Bioinformatics. 2004 Jan 22;20(2):271-3. doi: 10.1093/bioinformatics/btg401.
UNLABELLED
ROSO is software to design optimal oligonucleotide probe sets for microarrays. Selected probes show no significant cross-hybridization, no stable secondary structures and their Tm are chosen to minimize the Tm variability of the probe set.
AVAILABILITY
The program is available on the internet. Sources are freely available, for non-profit use, on request to the authors.
SUPPLEMENTARY INFORMATION
未标注
ROSO是一款用于设计微阵列最佳寡核苷酸探针集的软件。所选探针无明显交叉杂交现象，无稳定二级结构，且其熔解温度经选择以使探针集的熔解温度变异性最小化。
可用性
该程序可在互联网上获取。如需用于非营利用途，可向作者索取免费的源代码。
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