Hanif Muzammil Z, Ghesani Munir, Shah Arshad A, Kasai Tokuo
Department of Nuclear Medicine, St Luke's-Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA.
Clin Nucl Med. 2004 Feb;29(2):93-5. doi: 10.1097/01.rlu.0000110747.73368.cb.
Atherosclerosis is an inflammatory process accumulating numerous inflammatory cells such as macrophages and lymphocytes. This cellular infiltrate has a high metabolic demand, which can be reflected on F-18 FDG positron emission tomographic (PET) imaging. The FDG uptake in atherosclerotic vessels is usually distinguishable as a result of its linear and continuous appearance and mild level of activity. However, occasionally, atherosclerotic plaques present themselves as focal "hot spots," which can be easily misinterpreted as malignancy. This report emphasizes atherosclerotic plaques as a potential pitfall while interpreting FDG scans. It also highlights the importance of radiographic correlation to avoid such an error.
动脉粥样硬化是一个炎症过程，会积聚大量炎症细胞，如巨噬细胞和淋巴细胞。这种细胞浸润具有很高的代谢需求，这可以在F-18氟代脱氧葡萄糖正电子发射断层扫描（PET）成像中体现出来。由于其呈线性且连续的外观以及轻度的活性水平，动脉粥样硬化血管中的氟代脱氧葡萄糖摄取通常是可辨别的。然而，偶尔动脉粥样硬化斑块会表现为局灶性“热点”，这很容易被误诊为恶性肿瘤。本报告强调在解读氟代脱氧葡萄糖扫描时，动脉粥样硬化斑块是一个潜在的陷阱。它还强调了影像学相关性对于避免此类错误的重要性。
