霍奇金淋巴瘤后的第二原发性乳腺癌。
Second primary breast cancer after Hodgkin's disease.
作者信息
Horwich A, Swerdlow A J
机构信息
Academic Unit of Radiotherapy and Oncology, The Royal Marsden NHS Trust and the Institute of Cancer Research, Downs Road, Sutton, Surrey SM2 5NG, UK.
出版信息
Br J Cancer. 2004 Jan 26;90(2):294-8. doi: 10.1038/sj.bjc.6601499.
Abstract
Although the potential carcinogenic risk of radiotherapy is well known, it has become clear that there is a particularly high risk of radiation-induced breast cancer in women treated for Hodgkin's disease at young ages. Thankfully, death from breast cancer in this population is uncommon, but it is important to understand factors contributing to the risk, including treatment parameters, and to develop a logical and efficient method for medical management of those at risk. In this minireview, we examine the evidence which should inform such a management policy.
摘要
虽然放射治疗潜在的致癌风险众所周知，但现已明确，年轻时接受霍奇金病治疗的女性患辐射诱发乳腺癌的风险特别高。幸运的是，该人群中因乳腺癌死亡的情况并不常见，但了解导致风险的因素（包括治疗参数）并制定一种合理有效的医疗管理方法对于高危人群非常重要。在这篇小型综述中，我们审视了可为这种管理策略提供依据的证据。
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