Al-Mutairi N, Al-Fouzan A, Nour-Eldin Osama
Dermatology Department, Farwaniya Hospital, Kuwait.
J Cutan Med Surg. 2004 Jan-Feb;8(1):16-8. doi: 10.1007/s10227-003-0103-3. Epub 2004 Jan 23.
Two females, one 28 years old and the other 32 years old, developed dusky red macules with pain and a burning sensation within 24 hours of receiving influenza vaccine. One patient had blisters within the lesion. A clinical diagnosis of fixed drug eruption (FDE) due to influenza vaccine was made. Histopathology was consistent with the diagnosis of FDE. The lesions subsided within 2 weeks of topical corticosteroid treatment. The diagnosis was confirmed by topical provocation test with influenza vaccine. A Medline search revealed these cases to be the second report of this kind of reaction due to influenza vaccine.
两名女性,一名28岁,另一名32岁,在接种流感疫苗后24小时内出现暗红色斑疹,伴有疼痛和烧灼感。其中一名患者皮损内有水泡。临床诊断为流感疫苗引起的固定性药疹(FDE)。组织病理学与FDE诊断相符。经局部使用皮质类固醇治疗,皮损在2周内消退。通过流感疫苗局部激发试验确诊。对医学文献数据库(Medline)的检索显示,这些病例是关于流感疫苗引起此类反应的第二篇报道。