Radhi J M
Department of Pathology, McMaster University, Hamilton, Ontario, Canada.
J Cutan Med Surg. 2004 Jan-Feb;8(1):23-4. doi: 10.1007/s10227-003-0107-z. Epub 2004 Jan 23.
Chondroid syringoma or mixed tumor of the skin is a rare epithelial tumor with eccrine differentiation. The variant with small tubular lumina is extremely uncommon.
Chondroid syringoma is usually present as a single subcutaneous nodule. This report describes a man with multiple scalp lesions exhibiting features of chondroid syringoma with small tubular lumina.
A Pathological examination of surgically resected multiple scalp nodules was carried out by routine histology and immunohistochemistry. The following antibodies were found: cytokeratin, epithelial membrane antigen, and vimentin.
Microscopic findings revealed multiple chondroid syringoma with small tubular lumina. The tumor cells were positive for high- and low-molecular-weight keratin, epithelial membrane antigen, and vimentin.
This is the first report of multiple chondroid syringoma with small tubular lumina.
软骨样汗管瘤或皮肤混合瘤是一种罕见的具有小汗腺分化的上皮性肿瘤。具有小管腔的变异型极为罕见。
软骨样汗管瘤通常表现为单个皮下结节。本报告描述了一名男性，其头皮出现多个病变，具有软骨样汗管瘤伴小管腔的特征。
通过常规组织学和免疫组织化学对手术切除的多个头皮结节进行病理检查。使用了以下抗体：细胞角蛋白、上皮膜抗原和波形蛋白。
显微镜检查发现多个具有小管腔的软骨样汗管瘤。肿瘤细胞对高分子量和低分子量角蛋白、上皮膜抗原及波形蛋白呈阳性反应。
这是首例关于多个具有小管腔的软骨样汗管瘤的报告。
