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犬狂犬病病毒脑膜脑脊髓炎的临床评估

Clinical evaluation of rabies virus meningoencephalomyelitis in a dog.

作者信息

Barnes Heidi L, Chrisman Cheryl L, Farina Lisa, Detrisac Carol J

机构信息

College of Veterinary Medicine, University of Florida, Gainesville, Florida 32610, USA.

出版信息

J Am Anim Hosp Assoc. 2003 Nov-Dec;39(6):547-50. doi: 10.5326/0390547.

DOI:10.5326/0390547
PMID:14736720
Abstract

A 6-month-old, female, mixed-breed dog presented for acute, progressive, flaccid paraplegia and bilateral pelvic-limb hyperesthesia. A lymphocytic pleocytosis with 366 mg/dL protein was found on cerebral spinal fluid (CSF) evaluation. Electromyography (EMG) demonstrated positive sharp waves and fibrillations in the left pelvic limb; the M wave of the left sciatic nerve was not obtainable by nerve stimulation. Seizures and dementia began during recovery from anesthesia. Six days after onset of paralysis, the dog was euthanized. Direct fluorescent antibody testing of the brain was positive for raccoon rabies virus. This case demonstrates clinical evaluation, CSF analysis, and EMG in an animal with rabies meningoencephalomyelitis.

摘要

一只6个月大的雌性混种犬因急性、进行性弛缓性截瘫和双侧后肢感觉过敏前来就诊。脑脊液(CSF)检查发现淋巴细胞增多,蛋白含量为366 mg/dL。肌电图(EMG)显示左后肢出现正锐波和纤颤;通过神经刺激无法获得左坐骨神经的M波。在麻醉恢复过程中出现癫痫发作和痴呆症状。瘫痪发作6天后,该犬实施安乐死。对大脑进行的直接荧光抗体检测显示浣熊狂犬病病毒呈阳性。本病例展示了狂犬病脑膜脑脊髓炎动物的临床评估、脑脊液分析和肌电图检查。

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