Institute of Military Veterinary, Academy of Military Medical Sciences, Changchun, China.
Epidemiol Infect. 2011 Oct;139(10):1453-6. doi: 10.1017/S0950268811001348. Epub 2011 Jul 25.
This study describes an outbreak of rabies in a flock of 110 sheep in Yangqu county, Shanxi province, China, in 2010. The flock, housed in a cave being used as a sheepfold, was attacked by a rabid dog, which resulted in 36 deaths over the following 2 days from the crushing and trampling caused by panic, and some 15 further deaths from rabies 2 weeks later. Rabies in the sheep was confirmed by the fluorescent antibody test (FAT) and RT-PCR. Rabies virus was isolated from the index dog brain and its N gene was partially sequenced (nucleotides 77-880). Results showed that the canine isolate (SXTYD01) was rabies virus with the N gene fragment 100% identical to that of the virus isolated from rabid sheep. This is the first confirmed sheep rabies outbreak in China. The clinical presentation of the disease is also described.
本研究描述了 2010 年中国山西省阳曲县一群 110 只羊发生的狂犬病暴发。这群羊被关在一个用作羊圈的洞穴里，被一只狂犬病狗袭击，随后的两天里，由于恐慌导致的挤压和踩踏，有 36 只羊死亡，约 15 只羊在两周后死于狂犬病。羊的狂犬病通过荧光抗体试验（FAT）和 RT-PCR 得到确认。狂犬病病毒从指数犬的大脑中分离出来，并对其 N 基因进行了部分测序（核苷酸 77-880）。结果表明，犬分离株（SXTYD01）为狂犬病病毒，其 N 基因片段与从狂犬病羊中分离出的病毒 100%相同。这是中国首例确诊的绵羊狂犬病暴发。本文还描述了该病的临床特征。
