Sun X, Deng S, Li R, Wang Z, Luo S, Jin X, Zhang W
Eye Microbiology Department, Beijing Institute of Ophthalmology, Beijing 100005, China.
Br J Ophthalmol. 2004 Feb;88(2):165-6. doi: 10.1136/bjo.2002.011205.
To study the distribution and shifting trends of bacterial keratitis.
The data of 2220 corneal isolates from 1 January 1989 to 31 December 1998 were reviewed retrospectively.
Positive culture was recovered in 490 isolates. Gram positive cocci and Gram negative bacilli represented 51% and 39.4%, respectively. Pseudomonas aeruginosa was the most common pathogen (32.2%). A gradual increase in the percentage of Gram positive cocci coupled with a decrease of Gram negative bacilli.
Pseudomonas aeruginosa and coaculase negative Staphylococcus were the most common pathogens in bacterial keratitis in north China.
研究细菌性角膜炎的分布及变化趋势。
回顾性分析1989年1月1日至1998年12月31日期间2220份角膜分离株的数据。
490份分离株培养呈阳性。革兰氏阳性球菌和革兰氏阴性杆菌分别占51%和39.4%。铜绿假单胞菌是最常见的病原体（32.2%）。革兰氏阳性球菌的百分比逐渐增加，而革兰氏阴性杆菌的百分比则下降。
铜绿假单胞菌和凝固酶阴性葡萄球菌是中国北方细菌性角膜炎最常见的病原体。
