Mirzadeh H, Abbasi F
Department of Medical Engineering, Amir Kabir University of Technology, P.O. Box 15875/4413, Tehran, Iran.
J Biomed Mater Res B Appl Biomater. 2004 Feb 15;68(2):191-8. doi: 10.1002/jbm.b.20011.
Surface and bulk modification techniques of polydimethylsiloxane (PDMS) polymers were used to develop a new intracochlear electrode that can closely hug the inner wall of scala tympani. Laser-induced surface grafting of poly (2-hydroxyethyl methacrylate) (PHEMA) and sequential method for preparation of interpenetrating polymer networks (IPNs) of PDMS/PHEMA were, respectively, used for surface and bulk modifications. The hydrogel content and water-uptake capability of the modified samples were optimized by Taguchi method for experimental design. The modified PDMS samples were examined by performing attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, water contact-angle measurement, and peel strength tests. The performances of actual-sized fabricated electrodes were assessed inside a transparent model of scala tympani, which was filled with saline. After a swelling process, the hydrophilic branch begins to elongate and detach from hydrophobic branch and pushes it toward the inner wall.