Adam David N, Cohen Paul D, Ghazarian Danny
Department of Medicine, University of Toronto, Ontario, Canada.
J Cutan Med Surg. 2003 Jul-Aug;7(4):333-8. doi: 10.1007/s10227-002-0127-0.
Necrolytic Migratory Erythema (NME) is a rarely encountered dermatologic condition. It is the characteristic feature of a paraneoplastic syndrome associated with neuroendocrine pancreatic tumors. A case of NME initially diagnosed and treated as psoriasis is reviewed. A review of the current literature regarding NME is also included.
The purpose of this report is to familiarize dermatologists with a rare and potentially fatal disorder. Early recognition of NME can lead to possible cure, while delayed identification of the disease is associated with metastatic disease and a poor prognosis for the patient.
When evaluating the patient who presents with a dermatitis and weight loss, it is important to exercise great caution. The differential diagnosis should be re-evaluated in a disease that is not responsive to first-line therapy before further treatment is considered.
坏死性游走性红斑（NME）是一种罕见的皮肤病。它是与神经内分泌胰腺肿瘤相关的副肿瘤综合征的特征性表现。本文回顾了一例最初被诊断为银屑病并接受治疗的NME病例。同时也对当前关于NME的文献进行了综述。
本报告的目的是让皮肤科医生熟悉一种罕见且可能致命的疾病。早期识别NME可能会带来治愈的可能，而疾病的延迟识别则与转移性疾病以及患者的不良预后相关。
在评估出现皮炎和体重减轻的患者时，务必格外谨慎。在考虑进一步治疗之前，对于一线治疗无反应的疾病，应重新评估鉴别诊断。
