Bewley A P, Ross J S, Bunker C B, Staughton R C
Department of Dermatology, Chelsea and Westminster Hospital, London, U.K.
Br J Dermatol. 1996 Jun;134(6):1101-4.
We report a patient with the glucagonoma syndrome and octreotide-resistant necrolytic migratory erythema (NME). The NME responded on two occasions to an intravenous infusion of essential fatty acids (EFA) and amino acids (AA). A deficit of serum EFA prior to treatment was corrected following the infusion, whilst plasma AA were low before and after treatment. These findings indicate that NME, in the glucagonoma syndrome, may respond to correction of the EFA deficit, and that NME may be a disease of EFA deficiency.
我们报告了一名患有胰高血糖素瘤综合征和对奥曲肽耐药的坏死性游走性红斑（NME）的患者。NME有两次对静脉输注必需脂肪酸（EFA）和氨基酸（AA）产生反应。治疗前血清EFA缺乏在输注后得到纠正，而血浆AA在治疗前后均较低。这些发现表明，胰高血糖素瘤综合征中的NME可能对EFA缺乏的纠正有反应，并且NME可能是一种EFA缺乏性疾病。
