Hatch Kathryn L, Motschi Herbert, Maibach Howard I
Department of Agricultural and Biosystems Engineering, University of Arizona, Tucson, AZ 85721-5724, USA.
Am J Contact Dermat. 2003 Dec;14(4):205-12.
Little evidence exists that dyes to which individuals are patch test positive are in those garments that they suspect cause their dermatitis, which makes diagnosis and management of colored-textile allergic contact dermatitis difficult.
We determined whether disperse dyes to which a patient suspected of having a colored garment-dye contact allergy were in the garment that the patient suspected to be the cause of his or her skin lesions.
Each patient was patch-tested with 12 disperse dyes in a commercial patch test series. Disperse dyes in the submitted garment(s) were identified. The dyes to which each patient was patch test positive were compared with the dyes identified in that patient's submitted fabric(s). When a dye appeared in both lists, a correlation was found.
Twenty-two of 32 garments received contained disperse dyes. In all, 35 different disperse dyes were identified. Twelve dyes elicited a reaction in at least one patient. Only nine patients were patch test positive to at least one dye identified in the fabric submitted. Dyes appearing in both lists were Blue 106 (8 times), Blue 124 (2 times), Yellow 3 (once), and Red 1 (once).
Dyes to which a patient was patch test positive were infrequently identified in the fabric suspected to be the cause of the skin lesions, which means that the next step will be to patch-test with fabric swatches and extracts of dye from the submitted garments.
几乎没有证据表明个体斑贴试验呈阳性的染料存在于他们怀疑导致其皮炎的衣物中，这使得彩色纺织品过敏性接触性皮炎的诊断和管理变得困难。
我们确定怀疑患有彩色衣物染料接触过敏的患者斑贴试验呈阳性的分散染料是否存在于患者怀疑是其皮肤病变病因的衣物中。
在商业斑贴试验系列中，用12种分散染料对每位患者进行斑贴试验。识别送检衣物中的分散染料。将每位患者斑贴试验呈阳性的染料与该患者送检织物中识别出的染料进行比较。当一种染料出现在两个列表中时，即发现存在相关性。
32件送检衣物中有22件含有分散染料。总共识别出35种不同的分散染料。12种染料在至少一名患者中引发了反应。只有9名患者对送检织物中识别出的至少一种染料斑贴试验呈阳性。两个列表中都出现的染料是蓝106（8次）、蓝124（2次）、黄3（1次）和红1（1次）。
在怀疑是皮肤病变病因的织物中很少能识别出患者斑贴试验呈阳性的染料，这意味着下一步将用送检衣物的织物样本和染料提取物进行斑贴试验。
