Molmeret Maëlle, Bitar Dina M, Han Lihui, Kwaik Yousef Abu
Department of Microbiology and Immunology, University of Louisville College of Medicine, Louisville, KY 40292, USA.
Microbes Infect. 2004 Jan;6(1):129-39. doi: 10.1016/j.micinf.2003.11.004.
Legionella pneumophila has become a paradigm for facultative intracellular pathogens that modulate biogenesis of their phagosomes into replicative niches. The ability to alter host cell biology and tailor it into a hospitable host for intracellular proliferation is at the crux of the mechanism of pathogenesis of Legionnaires' disease.
嗜肺军团菌已成为兼性细胞内病原体的典范，这类病原体可将其吞噬体的生物发生调节为复制龛。改变宿主细胞生物学特性并将其转变为有利于细胞内增殖的适宜宿主的能力，是军团病发病机制的关键所在。
