西他司丁B的N-取代衍生物的合成与活性
Syntheses and activities of N-substituted derivatives of siastatin B.
作者信息
Kudo T, Nishimura Y, Kondo S, Takeuchi T
机构信息
Institute of Microbial Chemistry, Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1992 Oct;45(10):1662-8. doi: 10.7164/antibiotics.45.1662.
PMID:1473994
Abstract
N-Substituted derivatives of siastatin B have been obtained by a chemical modification. Some derivatives showed potent inhibitory activities against Streptococcus sp. and Clostridium perfringens neuraminidases.
摘要
通过化学修饰获得了西他司丁B的N-取代衍生物。一些衍生物对链球菌属和产气荚膜梭菌神经氨酸酶显示出强大的抑制活性。
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