Wu Dezheng, Jiang Futian, Liang Jiongji, Ma Jin, Luo Guangwei, Wen Feng, Wu Lezheng
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, 510060, China.
Yan Ke Xue Bao. 2003 Dec;19(4):253-6.
To evaluate the visual function in different area at retinal posterior pole for the patients with cystoid macular edema (CME).
Multifocal ERG was tested using visual evoked response imaging system (VERIS) 4.0 for 24 patients (27 eyes) with CME and 25 normal control subjects whose ages matched patient's ages, the traces and 3D function maps of first order kernel response were recorded on 103 retinal locations of 26.6 degrees X22.1 degrees visual field.
The latencies of N1 and P1 waves were remarkably prolonged at whole area and the 6 rings in the CME, there were statistically significant differences between the normal control group and CME (P < 0.01). Compared with normal control group, the average response densities of N1 wave at 1, 2, and 3 rings in the CME were seriously reduced (P < 0.01), but they in 4, 5 and 6 rings were not significantly changed (P > 0.05), the average response densities of P1 at whole area and the 6 rings were reduced (P < 0.05).
The mfERG is a promising tool to evaluate the visual function in different area at retinal posterior pole for the patients with CME. The response densities of N1 wave are better analysis index for CME.
评估黄斑囊样水肿（CME）患者视网膜后极部不同区域的视功能。
使用视觉诱发电位成像系统（VERIS）4.0对24例（27只眼）CME患者和25名年龄匹配的正常对照者进行多焦视网膜电图（mfERG）检查，在26.6度×22.1度视野的103个视网膜位点记录一阶核反应的波形和三维功能图。
CME患者整个区域及6个环带的N1波和P1波潜伏期均显著延长，正常对照组与CME组之间差异有统计学意义（P<0.01）。与正常对照组相比，CME患者1、2、3环带N1波的平均反应密度严重降低（P<0.01），而4、5、6环带无明显变化（P>0.05），整个区域及6个环带P1波的平均反应密度均降低（P<0.05）。
mfERG是评估CME患者视网膜后极部不同区域视功能的一种有前景的工具。N1波反应密度是分析CME更好的指标。
