Muntinga J H, Visser K R
Department of Medical Physiology, University of Groningen, The Netherlands.
J Appl Physiol (1985). 1992 Nov;73(5):1946-57. doi: 10.1152/jappl.1992.73.5.1946.
In 13 healthy volunteers a computerized experimental set-up was used to measure the electrical impedance of the upper arm at changing cuff pressure, together with the finger arterial blood pressure in the contralateral arm. On the basis of a model for the admittance response, the arterial blood volume per centimeter length (1.4 +/- 0.3 ml/cm), the venous blood volume as a percentage of the total blood compartment (49.2 +/- 12.6%), and the total arterial compliance as a function of mean arterial transmural pressure were estimated. The effective physiological arterial compliance amounted to 2.0 +/- 1.3 microliters.mmHg-1.cm-1 and the maximum compliance to 33.4 +/- 12.0 microliters.mmHg-1.cm-1. Additionally, the extravascular fluid volume expelled by the occluding cuff (0.3 +/- 0.3 ml/cm) was estimated. These quantities are closely related to patient-dependent sources of an unreliable blood pressure measurement and vary with changes in cardiovascular function, such as those found in hypertension. Traditionally, a combination of several methods is needed to estimate them. Such methods, however, usually neglect the contribution of extravascular factors.
在13名健康志愿者中，使用计算机化实验装置在改变袖带压力时测量上臂的电阻抗，并同时测量对侧手臂的手指动脉血压。基于导纳响应模型，估计了每厘米长度的动脉血容量（1.4±0.3 ml/cm）、静脉血容量占总血容量的百分比（49.2±12.6%）以及作为平均动脉跨壁压函数的总动脉顺应性。有效生理动脉顺应性为2.0±1.3微升·mmHg⁻¹·cm⁻¹，最大顺应性为33.4±12.0微升·mmHg⁻¹·cm⁻¹。此外，还估计了由阻塞袖带排出的血管外液体积（0.3±0.3 ml/cm）。这些量与血压测量不可靠的患者相关因素密切相关，并随心血管功能的变化而变化，如在高血压中发现的变化。传统上，需要多种方法相结合来估计它们。然而，这些方法通常忽略了血管外因素的贡献。
