一株来自加纳的恶性疟原虫适应夜猴属灰肢夜猴、南氏夜猴和尖吻夜猴的过程。
Adaptation of a strain of Plasmodium falciparum from Ghana to Aotus lemurinus griseimembra, A. nancymai, and A. vociferans monkeys.
作者信息
Sullivan Joann S, Sullivan James J, Williams Allison, Grady Katharine K, Bounngaseng Amy, Huber Curtis S, Nace Douglas, Williams Tyrone, Galland G Gale, Barnwell John W, Collins William E
机构信息
Division of Parasitic Diseases and Animal Resources Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
出版信息
Am J Trop Med Hyg. 2003 Dec;69(6):593-600.
A strain of Plasmodium falciparum from Ghana was adapted to Aotus lemurinus griseimembra, A. nancymai, and A. vociferans monkeys. Gametocytes in splenectomized A. nancymai were infective to Anopheles freeborni mosquitoes. Sporozoite transmission was accomplished in two splenectomized A. nancymai with prepatent periods of 22 and 25 days. The Ghana III/CDC strain of P. falciparum is susceptible to treatment with chloroquine and mefloquine.
来自加纳的一株恶性疟原虫适应了灰肢夜猴、南氏夜猴和叫夜猴。脾切除的南氏夜猴体内的配子体可感染弗里氏按蚊。在两只脾切除的南氏夜猴中完成了子孢子传播，潜伏期分别为22天和25天。恶性疟原虫加纳III/疾病控制中心株对氯喹和甲氟喹治疗敏感。
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