Nseir S, Pronnier P, Soubrier S, Onimus T, Saulnier F, Mathieu D, Durocher A
Service de Réanimation Médicale, Hôpital Calmette, CHRU, boulevard du Pr Leclercq, F-59037 Lille cedex, France.
Br J Anaesth. 2004 Mar;92(3):427-9. doi: 10.1093/bja/aeh065. Epub 2004 Jan 22.
A 74-yr-old diabetic woman developed necrotizing fasciitis of the right upper limb after axillary brachial plexus block for carpal tunnel decompression. Clinical signs included oedema, diffuse swelling and bullae; rapidly followed by toxic shock syndrome and multiorgan failure. The patient died 48 h after hospital admission, despite broad-spectrum antibiotics, surgical treatment and supportive measures for the management of shock and multiorgan failure. Cultures yielded group A Streptococcus. Delay in antibiotic and surgical treatment probably affected the outcome. Early diagnosis and treatment are essential to improve the outcome of streptococcal necrotizing fasciitis.