多系统萎缩中α-突触核蛋白阳性胶质细胞胞质内含物的空间模式
Spatial patterns of alpha-synuclein positive glial cytoplasmic inclusions in multiple system atrophy.
作者信息
Armstrong Richard A, Lantos Peter L, Cairns Nigel J
机构信息
Vision Sciences, Aston University, Birmingham, United Kingdom.
出版信息
Mov Disord. 2004 Jan;19(1):109-12. doi: 10.1002/mds.10637.
PMID:14743371
Abstract
In cases of multiple system atrophy (MSA), glial cytoplasmic inclusions (GCI) were distributed randomly or present in large diffuse clusters (>1,600 microm in diameter) in most areas studied. These spatial patterns contrast with those reported for filamentous neuronal inclusions in the tauopathies and alpha-synucleinopathies.
摘要
在多系统萎缩（MSA）病例中，胶质细胞胞质内包涵体（GCI）在大多数研究区域随机分布或呈大的弥漫性簇状存在（直径>1600微米）。这些空间模式与在tau蛋白病和α-突触核蛋白病中报道的丝状神经元包涵体的模式形成对比。
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