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输尿管镜检查治疗输尿管下段结石后常规置入支架不必要:一项随机对照试验的结果

Routine stenting after ureteroscopy for distal ureteral calculi is unnecessary: results of a randomized controlled trial.

作者信息

Srivastava Aneesh, Gupta Rajshekhar, Kumar Anant, Kapoor Rakesh, Mandhani Anil

机构信息

Department of Urology and Renal Transplantation, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Rai Bareilly Road, Lucknow (U.P.), India 226-014.

出版信息

J Endourol. 2003 Dec;17(10):871-4. doi: 10.1089/089277903772036172.

Abstract

BACKGROUND AND PURPOSE

Insertion of a ureteral stent is routinely done after ureteroscopy. Recently, several authors have questioned routine stenting after ureteroscopy for distal ureteral stones. We report our results of a randomized study comparing ureteroscopy with and without placement of stents for distal ureteral stones.

PATIENTS AND METHODS

A total of 48 patients undergoing ureteroscopy for distal ureteral stones were randomized to a stented group (N = 26) or a nonstented group (N = 22). Ureteroscopy was carried out with Wolf 8.5F semirigid endoscope, and the Swiss Lithoclast was used as the source of energy. Any stent was removed at 3 weeks. Patients were assessed for success, operative time, postoperative pain score, analgesic requirement, stent-related symptoms, and risk of ureteral stricture formation. Baseline variables were not significantly different in the two groups.

RESULTS

There was no significant difference in the two treatment groups with regard to need for ureteral dilation, use of intracorporeal lithotripsy, or occurrence of intraoperative and postoperative complications. A successful outcome was achieved in 100% of both groups. The mean pain score on day 0 was 5.23 +/- 0.95 of 10 in the stented group and 4.82 +/- 0.96 in the nonstented group; this difference was not statistically significant. Similarly, the analgesic requirement in the two treatment groups was not significantly different. However, patients with stents had significantly more pain (including flank pain with voiding: P = 0.01), urgency (P = 0.04) and dysuria (P <0.01). Radiologic follow-up was available for 83.33% of the patients at the 3-month visit. None of the patients had evidence of ureteral stricture or residual stone fragments.

CONCLUSION

In select patients undergoing ureteroscopy for distal ureteral stones, stents can be safely omitted. Patients without stents have significantly fewer lower-urinary symptoms of pain, urgency, and dysuria and are not at risk of increased complications. Avoiding stents may be particularly cost effective in developing countries.

摘要

背景与目的

输尿管镜检查术后常规置入输尿管支架。最近,几位作者对输尿管镜检查治疗远端输尿管结石后常规放置支架提出质疑。我们报告了一项随机研究的结果,该研究比较了输尿管镜检查治疗远端输尿管结石时放置支架与不放置支架的情况。

患者与方法

总共48例因远端输尿管结石接受输尿管镜检查的患者被随机分为支架置入组(N = 26)和无支架组(N = 22)。使用Wolf 8.5F半硬性内窥镜进行输尿管镜检查,并使用瑞士碎石机作为能量源。3周时取出所有支架。对患者的治疗成功率、手术时间、术后疼痛评分、镇痛需求、支架相关症状以及输尿管狭窄形成风险进行评估。两组的基线变量无显著差异。

结果

两组在输尿管扩张需求、体内碎石术的使用或术中及术后并发症的发生方面无显著差异。两组的治疗成功率均为100%。支架置入组第0天的平均疼痛评分为5.23±0.95(满分10分),无支架组为4.82±0.96;这种差异无统计学意义。同样,两个治疗组的镇痛需求无显著差异。然而,有支架的患者疼痛(包括排尿时侧腹疼痛:P = 0.01)、尿急(P = 0.04)和排尿困难(P <0.01)明显更多。83.33%的患者在3个月随访时有影像学检查结果。所有患者均无输尿管狭窄或残留结石碎片的证据。

结论

对于部分因远端输尿管结石接受输尿管镜检查的患者,可以安全地不放置支架。无支架的患者下尿路疼痛、尿急和排尿困难症状明显较少,且并发症风险未增加。在发展中国家,避免放置支架可能特别具有成本效益。

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