Wu Sheng Ping, Ringgaard Steffen, Oyre Sten, Hansen Michael S, Rasmus Stokholm, Pedersen Erik M
MR-Center, Institute of Experimental Clinical Research, Aarhus University Hospital, Aarhus, Denmark.
J Magn Reson Imaging. 2004 Feb;19(2):188-93. doi: 10.1002/jmri.10441.
To investigate wall shear rates in vivo in the common carotid, brachial, and superficial femoral arteries using very high resolution magnetic resonance imaging (MRI) phase contrast measurements.
Mean, maximum, and minimum wall shear rate and an oscillatory shear index were measured for 20 volunteers, aged 23.3 +/- 1.9 years, in the three arteries, using phase contrast imaging with 0.0625 mm2 resolution and three-dimensional paraboloid fitting.
The superficial femoral artery had the lowest mean (130.3 +/- 13.1 second(-1)), maximum (735.8 +/- 32.4 second(-1)), and minimum (-224.5 +/- 17.0 second(-1)) wall shear rate, as well as the highest oscillatory shear index (0.21 +/- 0.02). All values were significantly different (P < 0.05) from both the brachial artery and the common carotid artery values. The highest mean (333.3 +/- 13.6 second(-1)) and minimum (117.9 +/- 24.5 second(-1)) wall shear rates and the lowest oscillatory shear index (0 +/- 0) were found in the common carotid artery.
It is possible to measure wall shear rate in vivo in different arteries using MRI with very high resolution. The findings exhibit the in vivo environment of wall shear rates and suggest a nonuniform distribution of wall shear rates throughout the arterial system.
使用超高分辨率磁共振成像（MRI）相位对比测量法研究颈总动脉、肱动脉和股浅动脉的体内壁面剪切率。
对20名年龄在23.3±1.9岁的志愿者，在上述三条动脉中使用分辨率为0.0625平方毫米的相位对比成像和三维抛物面拟合测量平均、最大和最小壁面剪切率以及振荡剪切指数。
股浅动脉的平均壁面剪切率（130.3±13.1秒⁻¹）、最大壁面剪切率（735.8±32.4秒⁻¹）和最小壁面剪切率（-224.5±17.0秒⁻¹）最低，振荡剪切指数最高（0.21±0.02）。所有这些值与肱动脉和颈总动脉的值均有显著差异（P<0.05）。颈总动脉的平均壁面剪切率最高（333.3±13.6秒⁻¹）、最小壁面剪切率最高（117.9±24.5秒⁻¹），振荡剪切指数最低（0±0）。
使用超高分辨率MRI能够测量不同动脉的体内壁面剪切率。这些发现展示了壁面剪切率的体内环境，并提示壁面剪切率在整个动脉系统中分布不均。
