Pantos Ioannis, Patatoukas Georgios, Efstathopoulos Efstathios P, Katritsis Demosthenes
Athens Euroclinic, Department of Cardiology, 9 Athanassiadou St, Athens 11521, Greece.
Expert Rev Cardiovasc Ther. 2007 Sep;5(5):927-38. doi: 10.1586/14779072.5.5.927.
There is growing evidence to suggest that endothelial biology and atherosclerosis depend on arterial wall shear stress (WSS). We review the existing literature on in vivo measurements of WSS in healthy individuals using phase-contrast MRI, which is a promising, noninvasive technique for determining various blood flow characteristics. WSS data exist for the following arteries: carotid, brachial, aorta and femoral. Measured values indicate that WSS is site specific, a finding which opposes the notion that physiological WSS values are maintained at a constant magnitude in all parts of the arterial system. Among the WSS values obtained at the same site by different investigators there is qualitative agreement; however, differences exist in absolute values mainly due to the dependence on the method used to obtain WSS values from velocity data.
越来越多的证据表明，内皮生物学和动脉粥样硬化取决于动脉壁剪切应力（WSS）。我们回顾了现有关于使用相位对比磁共振成像对健康个体进行WSS体内测量的文献，这是一种用于确定各种血流特征的有前景的非侵入性技术。以下动脉存在WSS数据：颈动脉、肱动脉、主动脉和股动脉。测量值表明WSS具有部位特异性，这一发现与生理WSS值在动脉系统所有部位保持恒定大小的观点相悖。在不同研究者于同一部位获得的WSS值之间存在定性一致性；然而，绝对值存在差异，主要是由于从速度数据获取WSS值所依赖的方法不同。
