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皮肤过度瘢痕形成的预防与治疗。

Prevention and treatment of excessive dermal scarring.

作者信息

Roseborough Ingrid E, Grevious Mark A, Lee Raphael C

机构信息

Department of Surgery, Pritzker School of Medicine, The University of Chicago, Chicago, IL 60637, USA.

出版信息

J Natl Med Assoc. 2004 Jan;96(1):108-16.

Abstract

Today, wound management to avoid excessive scar formation is increasingly important, especially in populations with Fitzpatrick 3 or higher skin pigmentation. Medical science and industrial development are devoting more effort toward understanding and offering better therapy to control scars. However, advances in scar management have been hampered by the confusing or ambiguous terminology. There is no consensus on what amount of post-traumatic skin scar formation is "normal" and what should be considered "hypertrophic". In the World Health Organization's ICD-9, there is no diagnostic code for hypertrophic scar--only keloid is listed. Yet, the medical and scientific literature distinguishes them as different conditions. Our experience suggests that the diagnosis of keloid disease is greatly over-rendered. For black patients, an elevated scar seems, by default, diagnosed as keloid by most. This confusion results in inappropriate management of scar formation, and occasionally contributes to decision making related to elective or cosmetic surgery. Given that patients are expecting better outcomes from wound care today than in the past, this review article attempts to capture the essential biological factors related to wound scar production and discusses treatment options and indications used by the authors.

摘要

如今,避免过度瘢痕形成的伤口管理愈发重要,尤其是在皮肤色素沉着为菲茨帕特里克3级或更高的人群中。医学科学和产业发展正投入更多精力来了解并提供更好的疗法以控制瘢痕。然而,瘢痕管理的进展一直受到术语混淆或模糊的阻碍。对于创伤后皮肤瘢痕形成多少算“正常”以及什么应被视为“增生性”,目前尚无共识。在世界卫生组织的《国际疾病分类第九版》(ICD - 9)中,没有增生性瘢痕的诊断编码——仅列出了瘢痕疙瘩。然而,医学和科学文献将它们视为不同的病症。我们的经验表明,瘢痕疙瘩疾病的诊断被过度做出。对于黑人患者,大多数情况下,隆起的瘢痕似乎默认被诊断为瘢痕疙瘩。这种混淆导致瘢痕形成的管理不当,偶尔还会影响与择期手术或美容手术相关的决策。鉴于如今患者期望伤口护理能比过去有更好的效果,这篇综述文章试图梳理与伤口瘢痕产生相关的关键生物学因素,并讨论作者所采用的治疗选择和适应症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5100/2594768/614b1948193f/jnma00301-0113-a.jpg

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