Hypocretin administration as a treatment for human narcolepsy.
作者信息
Siegel J M
出版信息
Sleep. 2003 Dec 15;26(8):932-3.
Abstract
摘要
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Pattern of hypocretin (orexin) soma and axon loss, and gliosis, in human narcolepsy.人类发作性睡病中下丘脑分泌素（食欲素）神经元胞体和轴突丢失以及胶质细胞增生的模式。
Brain Pathol. 2003 Jul;13(3):340-51. doi: 10.1111/j.1750-3639.2003.tb00033.x.
2
Intravenously administered hypocretin-1 alters brain amino acid release: an in vivo microdialysis study in rats.静脉注射下丘脑分泌素-1可改变脑内氨基酸释放：一项大鼠体内微透析研究
J Physiol. 2003 Apr 15;548(Pt 2):557-62. doi: 10.1113/jphysiol.2002.038729. Epub 2003 Mar 7.
3
Arousal effects of orexin-A correlate with GLU release from the locus coeruleus in rats.食欲肽A的唤醒作用与大鼠蓝斑中谷氨酸的释放相关。
Peptides. 2002 Sep;23(9):1673-81. doi: 10.1016/s0196-9781(02)00109-2.
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Release of hypocretin (orexin) during waking and sleep states.清醒和睡眠状态下下丘脑分泌素（食欲素）的释放。
J Neurosci. 2002 Jul 1;22(13):5282-6. doi: 10.1523/JNEUROSCI.22-13-05282.2002.
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A neural circuit for circadian regulation of arousal.一种用于昼夜节律调节觉醒的神经回路。
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Differential expression of orexin receptors 1 and 2 in the rat brain.大鼠脑中食欲素受体1和2的差异表达。
J Comp Neurol. 2001 Jun 18;435(1):6-25. doi: 10.1002/cne.1190.
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Increased and decreased muscle tone with orexin (hypocretin) microinjections in the locus coeruleus and pontine inhibitory area.在蓝斑和脑桥抑制区微量注射食欲素（下丘脑泌素）后肌张力的升高和降低。
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Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation.食欲素-A诱导胃酸分泌需要完整的二硫键，该过程由OX1受体激活介导。
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10
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Neuron. 2000 Sep;27(3):469-74. doi: 10.1016/s0896-6273(00)00058-1.
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