Kwon Hyuk-Sang, Cho Jae-Hyoung, Kim Hee-Soo, Song Bok-Re, Ko Seung-Hyun, Lee Jung-Min, Kim Sung-Rae, Chang Sang-Ah, Kim Hee-Seung, Cha Bong-Yun, Lee Kwang-Woo, Son Ho-Young, Lee Jin-Hee, Lee Won-Chul, Yoon Kun-Ho
Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea.
Diabetes Care. 2004 Feb;27(2):478-83. doi: 10.2337/diacare.27.2.478.
The Internet is used worldwide as a communication tool. To improve the quality of diabetes control, we investigated the effectiveness of an Internet-based blood glucose monitoring system (IBGMS) on controlling the changes in HbA(1c) levels.
We conducted a randomized clinical trial involving 110 patients who visited the outpatient clinic at the Kangnam St. Mary's Hospital for 3 months. The study subjects were treated with IBGMS for 12 weeks, and the control group received the usual outpatient management over the same period. HbA(1c) and other laboratory tests were performed twice, once at the beginning of the study and again at the end of the study.
The test results from the beginning of the study established that there were no significant differences between the two groups with respect to age, sex, diabetes duration, BMI, blood pressure, HbA(1c), and other laboratory data. On follow-up examination 12 weeks later, HbA(1c) levels were significantly decreased from 7.59 to 6.94% within the intervention group (P < 0.001). At the end of the study, HbA(1c) levels in the intervention group were significantly lower than in the control group after adjusting the baseline HbA(1c) (6.94 vs. 7.62%; P < 0.001, respectively). Among patients with baseline HbA(1c) <7.0%, the patients in the intervention group had lower HbA(1c) than those in the control group (6.38 vs. 6.99%; P < 0.05). Among the patients with a baseline HbA(1c) > or = 7.0%, the difference between the two groups appeared more obvious: HbA(1c) levels at the end of the study were 8.12%.
This new IBGMS resulted in a significant reduction of HbA(1c) during the study period. We propose that this IBGMS be used as a method for improving diabetes control.
互联网在全球范围内被用作一种通信工具。为提高糖尿病控制质量，我们研究了基于互联网的血糖监测系统（IBGMS）对控制糖化血红蛋白（HbA1c）水平变化的有效性。
我们进行了一项随机临床试验，涉及110名在江南圣母医院门诊就诊3个月的患者。研究对象接受IBGMS治疗12周，对照组在同一时期接受常规门诊管理。糖化血红蛋白（HbA1c）和其他实验室检查进行了两次，一次在研究开始时，一次在研究结束时。
研究开始时的测试结果表明，两组在年龄、性别、糖尿病病程、体重指数、血压、糖化血红蛋白（HbA1c）和其他实验室数据方面无显著差异。12周后的随访检查显示，干预组的糖化血红蛋白（HbA1c）水平从7.59%显著降至6.94%（P<0.001）。研究结束时，调整基线糖化血红蛋白（HbA1c）后，干预组的糖化血红蛋白（HbA1c）水平显著低于对照组（分别为6.94%和7.62%；P<0.001）。在基线糖化血红蛋白（HbA1c）<7.0%的患者中，干预组患者的糖化血红蛋白（HbA1c）低于对照组（6.38%对6.99%；P<0.05）。在基线糖化血红蛋白（HbA1c）≥7.0%的患者中，两组之间的差异更为明显：研究结束时糖化血红蛋白（HbA1c）水平为8.12%。
这种新的IBGMS在研究期间导致糖化血红蛋白（HbA1c）显著降低。我们建议将这种IBGMS用作改善糖尿病控制的一种方法。
