Formiga F, Chivite D, Manito N, Osma V, Miravet S, Pujol R
Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
QJM. 2004 Feb;97(2):81-6. doi: 10.1093/qjmed/hch018.
Outcomes related to heart failure remain relatively poor.
To examine the clinical course of patients for one year after their first admission because of heart failure, including prognosis, mortality, and rehospitalization.
Prospective observational study.
Of 121 patients hospitalized over 6 months for decompensation of previously unknown heart failure, we excluded those with a possible previous diagnosis of heart failure (n = 5), who suffered from another serious disease with a poor prognosis (n = 6), died during the index hospitalization (n = 5), refused to participate (n = 4) or were lost to follow-up (n = 6). Mortality and readmissions were identified by prospective follow-up of all patients.
Of the 98 patients evaluated, half (49) were women. Mean +/- SD age was 75.2 +/- 12 years. The 1-year case-fatality rate after the first admission was 24%; 19% of the deaths were heart failure-related, with progressive pump failure the predominant cause (14% of the total). Age was the only factor associated with increased mortality (p < 0.007). Of the 74 survivors, 32% experienced at least one hospital readmission during follow-up.
The prognosis of unselected new cases of heart failure after their first hospitalization remains relatively poor, despite recent advances in pharmacological therapy and medical care.
与心力衰竭相关的预后仍然相对较差。
研究因心力衰竭首次入院后患者的一年临床病程,包括预后、死亡率和再住院情况。
前瞻性观察性研究。
在121例因先前未知的心力衰竭失代偿而住院超过6个月的患者中,我们排除了那些可能先前已诊断为心力衰竭的患者(n = 5)、患有另一种预后不良的严重疾病的患者(n = 6)、在索引住院期间死亡的患者(n = 5)、拒绝参与的患者(n = 4)或失访的患者(n = 6)。通过对所有患者的前瞻性随访确定死亡率和再入院情况。
在98例接受评估的患者中,一半(49例)为女性。平均年龄±标准差为75.2±12岁。首次入院后的1年病死率为24%;19%的死亡与心力衰竭相关,主要原因是进行性泵衰竭(占总数的14%)。年龄是与死亡率增加相关的唯一因素(p < 0.007)。在74名幸存者中,32%在随访期间至少经历了一次再次住院。
尽管近期药物治疗和医疗护理取得了进展,但未经选择的心力衰竭新病例首次住院后的预后仍然相对较差。