Mannan M A, Rahman M S, Siddiqui N I
Department of Endocrinology & Metabolism, Sir Salimullah Medical College, Mitford Hospital, Dhaka-1100.
Mymensingh Med J. 2004 Jan;13(1):95-9.
Obesity infrequently associated with type 2 diabetes mellitus and may cause insulin resistance, hypertension and other complications of obesity. So obesity management in Type 2 diabetes mellitus is essential. Prevention is a logical first step in the management of the obese Type 2 diabetic patient, such programs have had little long-term success. Diet, exercise and behavioral modification still form the cornerstones of treatment and relatively small weight loss results in improvement of all major obesity related co-morbidity's, including Type 2 diabetes. The obese diabetic patient faces extra impediments to weight loss, including the adverse effects of diabetic medication, poor glycaemic control and diabetes related complications. New drugs may offer some additional help, in general by providing the benefit associated with the weight loss as such, Bariatric surgery can produce major long-term weight loss in the severely obese subjects.
肥胖很少与2型糖尿病相关联，但可能导致胰岛素抵抗、高血压及其他肥胖并发症。因此，2型糖尿病患者的肥胖管理至关重要。预防是肥胖2型糖尿病患者管理中合乎逻辑的第一步，但此类方案长期成功率较低。饮食、运动和行为改变仍是治疗的基石，相对少量的体重减轻就能改善所有与肥胖相关的主要合并症，包括2型糖尿病。肥胖糖尿病患者在减肥方面面临额外障碍，包括糖尿病药物的不良反应、血糖控制不佳及糖尿病相关并发症。新药可能会提供一些额外帮助，一般是通过带来与体重减轻相关的益处，减肥手术可使严重肥胖者实现显著的长期体重减轻。
