Kogut B M, Voĭtenko E V, Korotenko V N
Khirurgiia (Mosk). 1992 Sep-Oct(9-10):16-9.
Nine groups of experiments were conducted on 120 rats and 55 dogs to study the morphological changes and the density of cholinergic nerve fibres in the intramural nerve apparatus of the stomach after cooling of the vagus nerves at various temperatures and time regimens of the exposure (-35-45 degrees, -70-80 degrees for 2-3 sec., 15 sec in one, two, and three exposures). The completeness of vagotomy was determined by the method of parietal pH measurement and modelling of stress-induced ulcers. It was established that depending on the thickness of the nerves and the regimen of the exposure to cooling, one can achieve total vagotomy with destructive changes in the nerve apparatus, incomplete vagotomy and transient inhibition-blockade of the acid-regulating function of vagus nerves with maintenance of the morphological and histochemical characteristics of intramural plexuses.
对120只大鼠和55只狗进行了九组实验，以研究在不同温度和暴露时间方案（-35 - 45摄氏度、-70 - 80摄氏度，暴露2 - 3秒，单次、两次和三次暴露15秒）下迷走神经冷却后胃壁内神经装置中胆碱能神经纤维的形态变化和密度。通过壁细胞pH测量方法和应激性溃疡建模来确定迷走神经切断的完整性。结果表明，根据神经的粗细和冷却暴露方案，可实现神经装置发生破坏性变化的完全迷走神经切断、不完全迷走神经切断以及迷走神经酸调节功能的短暂抑制 - 阻断，同时壁内神经丛的形态和组织化学特征得以保留。
