Heini P F, Orler R
Orthopädische Universitätsklinik, Inselspital, Bern, Schweiz.
Orthopade. 2004 Jan;33(1):22-30. doi: 10.1007/s00132-003-0574-3.
In severe osteoporosis progressive collapse of multiple vertebrae is an unsolved problem. Medical treatment appears to be too slow to prevent the course. The evolving experience with vertebroplasty led us to treat these problems with more extensive cement injections. Of 362 patients who were treated with percutaneous cement injection over a 5-year period, 100 were injected at five and more levels (average 7.3, maximum 14). The surgical technique has been refined, allowing six levels to be injected monolaterally under local anesthesia. No more than six levels or 25-30 cc of cement should be injected per session. The outcome of the procedure is favorable in 84% of patients with a significant pain decrease (from 7.6 to 2.7 VAS). More impressive is the subjective report of the patients about better posture and increased force in their back, allowing them to become more active again. The radiological follow-up for 1 year shows a stable situation without further sintering of the reinforced vertebrae and maintained disc space in between these vertebrae. Vertebroplasty on multiple levels is efficient and can prevent further collapse. Due the risk of fat embolism the injections should be limited to six levels per session.
在严重骨质疏松症中,多个椎体的进行性塌陷是一个尚未解决的问题。药物治疗似乎起效过慢,无法阻止病情发展。椎体成形术不断发展的经验促使我们通过更广泛的骨水泥注射来治疗这些问题。在5年期间接受经皮骨水泥注射治疗的362例患者中,100例接受了五个及以上节段的注射(平均7.3个节段,最多14个节段)。手术技术已得到改进,可在局部麻醉下单侧注射六个节段。每次注射节段不应超过六个或骨水泥量不应超过25 - 30立方厘米。该手术在84%的患者中效果良好,疼痛显著减轻(视觉模拟评分从7.6降至2.7)。更令人印象深刻的是患者主观报告称姿势改善,背部力量增强,从而能够再次更加活跃。1年的影像学随访显示情况稳定,强化椎体没有进一步骨化,椎体间椎间盘间隙保持良好。多节段椎体成形术有效,可防止进一步塌陷。由于存在脂肪栓塞风险,每次注射应限于六个节段。