Strauss Roland M, Orton David I
Environmental and Contact Dermatitis Unit, Amersham Hospital, Whielden Street, Amersham, Buckinghamshire, HP7 0JD, United Kingdom.
Am J Contact Dermat. 2003 Jun;14(2):75-7.
To date, only a few cohorts of patients with allergic cheilitis have been described, most of them from Australia and Asia.
To establish the prevalence of cheilitis in a UK specialist contact dermatitis clinic and to identify the most common allergens.
We analyzed our patch-test database in a tertiary referral center in the United Kingdom, retrospectively. All patients presenting with cheilitis over a 19-year period (1982 to 2001) were included.
Data were available from a total of 146 patients. A positive allergic patch-test reaction was thought to be relevant in 15% of the patients (n = 22) and to be of possible relevance in 6.8% (n = 10). Of the 22 patients with relevant allergic results, 95% (n = 21) were women. The most common allergens included fragrance mix (mainly cinnamaldehyde, oak moss, and isoeugenol) in 41% of patients, shellac in 18%, colophony in 18%, and Myroxylon pereirae in 14%. For half of the patients, the allergen was believed to stem from lipsticks or lip products. Eighteen percent of patients with allergic cheilitis reacted to only their own products.
Patients should be tested to extended lipstick/cosmetic vehicle series in addition to standard series. As a significant percentage of patients react to their own products only, a thorough clinical history and testing to patients' own products are important.
迄今为止，仅有少数几例变应性唇炎患者队列被描述，其中大多数来自澳大利亚和亚洲。
确定英国一家专科接触性皮炎诊所中唇炎的患病率，并识别最常见的变应原。
我们对英国一家三级转诊中心的斑贴试验数据库进行了回顾性分析。纳入了在19年期间（1982年至2001年）出现唇炎的所有患者。
共有146例患者的数据可用。15%（n = 22）的患者斑贴试验变应性反应被认为具有相关性，6.8%（n = 10）的患者被认为可能具有相关性。在22例变应性结果具有相关性的患者中，95%（n = 21）为女性。最常见的变应原包括香料混合物（主要为肉桂醛、橡苔和异丁香酚），41%的患者对其过敏；虫胶，18%；松香，18%；秘鲁香脂，14%。对于一半的患者，变应原被认为源于口红或唇部产品。18%的变应性唇炎患者仅对自己的产品有反应。
除标准系列外，还应对患者进行扩展的口红/化妆品基质系列检测。由于相当比例的患者仅对自己的产品有反应，详细的临床病史以及对患者自身产品的检测很重要。
