From the The Skin Hospital, Sydney.
The University of Sydney, Australia.
Dermatitis. 2019 Nov/Dec;30(6):347-351. doi: 10.1097/DER.0000000000000524.
The etiology of cheilitis includes endogenous, irritant, and allergic dermatitis; lichenoid and granulomatous disorders; infection; trauma; and actinic damage. Patch testing is indicated for refractory cases (other than actinic cheilitis).
The aim of the study was to review demographics and allergens in patients patch tested for cheilitis at 2 sites in Sydney, Australia.
Records for patients patch tested for a 10-year period from 2007 to 2017 were reviewed. Baseline characteristics and patch test results were compared for patients with and without cheilitis.
There were 1584 patients including 91 with cheilitis. Patients with cheilitis were more likely to be female, younger, and atopic and have concurrent eyelid involvement than those presenting with other dermatoses. Seventeen percent of patients with cheilitis had a post-patch test diagnosis of allergic contact cheilitis, and the most frequent relevant reactions were to patients' own products, fragrances, and sunscreens. Those with cheilitis had more positive reactions to sunscreens, especially benzophenones, compared with those without cheilitis (P < 0.001). This is an important finding in Australia where high rates of melanoma and nonmelanoma skin cancer necessitate promotion of strict sun protection measures.
唇炎的病因包括内源性、刺激性和过敏性皮炎；苔藓样和肉芽肿性疾病；感染；创伤；和光损伤。斑贴试验适用于难治性病例（光化性唇炎除外）。
本研究旨在回顾 2007 年至 2017 年在澳大利亚悉尼的 2 个地点进行唇炎斑贴试验的患者的人口统计学和过敏原。
回顾了 10 年来（2007 年至 2017 年）接受斑贴试验的患者的记录。比较了唇炎患者和其他皮肤病患者的基线特征和斑贴试验结果。
共有 1584 名患者，其中 91 名患有唇炎。与其他皮肤病患者相比，唇炎患者更可能是女性、年轻、特应性且伴有眼睑受累。17%的唇炎患者在斑贴试验后被诊断为过敏性接触性唇炎，最常见的相关反应是患者自身产品、香料和防晒霜。与没有唇炎的患者相比，唇炎患者对防晒霜的阳性反应更多，尤其是对苯并酮（P<0.001）。这是澳大利亚的一个重要发现，因为那里黑色素瘤和非黑色素瘤皮肤癌的发病率很高，需要推广严格的防晒措施。
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