• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

马来西亚沙巴和砂拉越军事人员中针对类鼻疽杆菌外毒素和全细胞抗原的抗体流行情况。

Prevalence of antibodies to Pseudomonas pseudomallei exotoxin and whole cell antigens in military personnel in Sabah and Sarawak, Malaysia.

作者信息

Embi N, Suhaimi A, Mohamed R, Ismail G

机构信息

Faculty of Life Sciences, Universiti Kebangsaan Malaysia, Bangi, Selangor.

出版信息

Microbiol Immunol. 1992;36(8):899-904. doi: 10.1111/j.1348-0421.1992.tb02092.x.

DOI:10.1111/j.1348-0421.1992.tb02092.x
PMID:1474938
Abstract

Sera from 420 military personnel serving in Sabah and Sarawk, Malaysia, were tested for antibodies to Pseudomonas pseudomallei exotoxin and whole cell antigens by enzyme-linked immunosorbent assay procedure (ELISA). Data showed that 54.4% of serum samples were positive for antibodies to P. pseudomallei exotoxin and 65.7% were positive for antibodies to the whole cell antigens. Samples gave much lower titers for anti-exotoxin antibodies compared to titers against crude whole cell antigens. The incidence of antibody to exotoxin was highest in the age groups ranging from 26 to 32 years, where the positive rates were higher than 40% and 30% for military personnel serving in Sarawak and Sabah, respectively.

摘要

对在马来西亚沙巴和砂拉越服役的420名军事人员的血清,采用酶联免疫吸附测定法(ELISA)检测抗类鼻疽假单胞菌外毒素和全细胞抗原的抗体。数据显示,54.4%的血清样本抗类鼻疽假单胞菌外毒素抗体呈阳性,65.7%的血清样本抗全细胞抗原抗体呈阳性。与抗粗制全细胞抗原的滴度相比,样本中抗外毒素抗体的滴度要低得多。外毒素抗体的发生率在26至32岁年龄组中最高,在砂拉越和沙巴服役的军事人员中,阳性率分别高于40%和30%。

相似文献

1
Prevalence of antibodies to Pseudomonas pseudomallei exotoxin and whole cell antigens in military personnel in Sabah and Sarawak, Malaysia.马来西亚沙巴和砂拉越军事人员中针对类鼻疽杆菌外毒素和全细胞抗原的抗体流行情况。
Microbiol Immunol. 1992;36(8):899-904. doi: 10.1111/j.1348-0421.1992.tb02092.x.
2
Antibody to Pseudomonas pseudomallei exotoxin in sheep exposed to natural infection.自然感染的绵羊体内抗类鼻疽杆菌外毒素抗体。
Vet Microbiol. 1991 May;27(3-4):277-82. doi: 10.1016/0378-1135(91)90154-8.
3
Indirect hemagglutination antibodies against Burkholderia pseudomallei in normal blood donors and suspected cases of melioidosis in Malaysia.马来西亚正常献血者及疑似类鼻疽病病例中抗伯克霍尔德菌的间接血凝抗体
Southeast Asian J Trop Med Public Health. 1996 Jun;27(2):263-6.
4
Melioidosis in Malaysia. 3. Antibodies to Pseudomonas pseudomallei in the human population.马来西亚的类鼻疽。3. 人群中针对类鼻疽杆菌的抗体。
Am J Trop Med Hyg. 1969 Sep;18(5):703-7.
5
An ELISA-disc procedure for antibodies toPseudomonas pseudomallei: application for a serological study of melioidosis in an endemic area.酶联免疫吸附试验(ELISA-disc)检测抗类鼻疽伯克霍尔德菌抗体的方法:在流行地区进行类鼻疽血清学研究的应用。
World J Microbiol Biotechnol. 1993 Jan;9(1):91-6. doi: 10.1007/BF00656525.
6
Serodiagnosis of melioidosis in Malaysia.
Singapore Med J. 1995 Jun;36(3):299-302.
7
Burkholderia thailandensis whole cell antigen cross-reacts with B. pseudomallei antibodies from patients with melioidosis in an immunofluorescent assay.在免疫荧光试验中,泰国伯克霍尔德菌全细胞抗原与类鼻疽病患者的假鼻疽伯克霍尔德菌抗体发生交叉反应。
Southeast Asian J Trop Med Public Health. 2010 Mar;41(2):395-400.
8
Monoclonal antibodies to Pseudomonas pseudomallei and their potential for diagnosis of melioidosis.针对类鼻疽杆菌的单克隆抗体及其在类鼻疽病诊断中的潜力。
Am J Trop Med Hyg. 1995 Mar;52(3):231-5. doi: 10.4269/ajtmh.1995.52.231.
9
Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis.使用粗抗原和纯化抗原的酶联免疫吸附测定法对类鼻疽进行血清学诊断的准确性。
Clin Vaccine Immunol. 2007 Jan;14(1):110-3. doi: 10.1128/CVI.00289-06. Epub 2006 Nov 8.
10
Production and evaluation of recombinant Burkholderia pseudomallei GroEL and OmpA proteins for serodiagnosis of melioidosis.用于类鼻疽血清诊断的重组伯克霍尔德菌假鼻疽菌GroEL和OmpA蛋白的制备与评估
Acta Trop. 2018 Feb;178:333-339. doi: 10.1016/j.actatropica.2017.10.019. Epub 2017 Oct 23.

引用本文的文献

1
Two Decades of Melioidosis in India: A Comprehensive Epidemiological Review.印度类鼻疽二十年:全面的流行病学综述
Pathogens. 2025 Apr 14;14(4):379. doi: 10.3390/pathogens14040379.
2
Estimation of seroprevalence of melioidosis among adult high risk groups in Southeastern India by indirect Hemagglutination assay.通过间接血凝试验评估印度东南部成年高危人群中类鼻疽病的血清阳性率。
PLOS Glob Public Health. 2022 May 9;2(5):e0000431. doi: 10.1371/journal.pgph.0000431. eCollection 2022.
3
Burden and Risk Factors of Melioidosis in Southeast Asia: A Scoping Review.
东南亚类鼻疽病的负担和危险因素:范围综述。
Int J Environ Res Public Health. 2022 Nov 22;19(23):15475. doi: 10.3390/ijerph192315475.
4
Human Melioidosis.类鼻疽病。
Clin Microbiol Rev. 2020 Mar 11;33(2). doi: 10.1128/CMR.00006-19. Print 2020 Mar 18.
5
Relapse of chronic melioidosis in a paediatric cystic fibrosis patient: first case report from Malaysia.马来西亚首例儿童囊性纤维化患者慢性类鼻疽病复发:病例报告。
BMC Infect Dis. 2018 Sep 5;18(1):455. doi: 10.1186/s12879-018-3371-7.
6
Pediatric melioidosis in Sarawak, Malaysia: Epidemiological, clinical and microbiological characteristics.马来西亚砂拉越州的小儿类鼻疽:流行病学、临床及微生物学特征
PLoS Negl Trop Dis. 2017 Jun 9;11(6):e0005650. doi: 10.1371/journal.pntd.0005650. eCollection 2017 Jun.
7
An ELISA-disc procedure for antibodies toPseudomonas pseudomallei: application for a serological study of melioidosis in an endemic area.酶联免疫吸附试验(ELISA-disc)检测抗类鼻疽伯克霍尔德菌抗体的方法:在流行地区进行类鼻疽血清学研究的应用。
World J Microbiol Biotechnol. 1993 Jan;9(1):91-6. doi: 10.1007/BF00656525.
8
Passive protection of diabetic rats with antisera specific for the polysaccharide portion of the lipopolysaccharide isolated from Pseudomonas pseudomallei.用针对从类鼻疽假单胞菌分离的脂多糖多糖部分的抗血清对糖尿病大鼠进行被动保护。
Can J Infect Dis. 1994 Jul;5(4):170-8. doi: 10.1155/1994/856850.