Pepple D J
Department of Human Physiology, College of Medical Sciences, University of Maiduguri, Nigeria.
Med Hypotheses. 1992 Nov;39(3):284-5. doi: 10.1016/0306-9877(92)90124-u.
The sickle cell trait has been reported to offer some protection against anaemia in pregnancy. Some attribute this to the break up of the cells which release iron for the synthesis of haemoglobin. The hypothesis presented here is that the 'partial' protective mechanism of the sickle cell trait is due to increased erythropoietic activity.
据报道，镰状细胞性状能为孕期贫血提供一定保护。有人将此归因于细胞破裂后释放铁用于合成血红蛋白。本文提出的假设是，镰状细胞性状的“部分”保护机制是由于红细胞生成活性增加。
