IRD UMR216, Mère et enfant face aux infections tropicales, Paris, France.
Trop Med Int Health. 2012 Mar;17(3):283-91. doi: 10.1111/j.1365-3156.2011.02932.x. Epub 2011 Dec 7.
To determine the effect of maternal anaemia on pregnancy outcome and describe its impact on infant haemoglobin level in the first 18 months of life, we conducted a prospective study of 617 pregnant women and their children in Benin. Prevalence of maternal anaemia at delivery was 39.5%, and 61.1% of newborns were anaemic at birth. Maternal anaemia was not associated with low birth weight [OR = 1.2 (0.6-2.2)] or preterm birth [OR = 1.3 (0.7-2.4)], whereas the newborn's anaemia was related to maternal anaemia [OR = 1.8 (1.2-2.5)]. There was no association between an infant's haemoglobin level until 18 months and maternal anaemia. However, malaria attacks during follow-up, male gender and sickle cell trait were all associated with a lower infant haemoglobin level until 18 months, whereas good infant feeding practices and a polygamous family were positively associated with a higher haemoglobin level during the first 18 months of life.
为了确定母体贫血对妊娠结局的影响，并描述其对婴儿出生后 18 个月内血红蛋白水平的影响，我们在贝宁对 617 名孕妇及其子女进行了一项前瞻性研究。分娩时母体贫血的患病率为 39.5%，61.1%的新生儿出生时贫血。母体贫血与低出生体重无关[比值比（OR）=1.2（0.6-2.2)]或早产[OR=1.3（0.7-2.4)]，而新生儿贫血与母体贫血有关[OR=1.8（1.2-2.5)]。婴儿出生后 18 个月时的血红蛋白水平与母体贫血之间没有关联。然而，在随访期间发生疟疾发作、男性性别和镰状细胞特征均与婴儿出生后 18 个月时的血红蛋白水平较低有关，而良好的婴儿喂养方式和一夫多妻家庭与前 18 个月的血红蛋白水平较高呈正相关。
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