MMWR Morb Mortal Wkly Rep. 2004 Jan 30;53(3):60-3.
During June 2001--March 2003, outbreaks of Shigella sonnei infections were reported in Delaware, Maryland, New Jersey, North Carolina, South Carolina, and Virginia. Five- to fortyfold increases in statewide shigellosis rates were observed during this period. These increases were attributed primarily to outbreaks in multiple day care settings that became prolonged and community wide. S. sonnei isolates from these states, as well as from New York City and Philadelphia, were similar genetically by pulsed-field gel electrophoresis (PFGE). Many of these isolates lacked the capacity to ferment rhamnose, which is unusual for S. sonnei. This report summarizes these outbreaks and describes the laboratory characteristics that link them. The findings underscore the importance of rapid and coordinated public health responses to isolated outbreaks of shigellosis.
在2001年6月至2003年3月期间，特拉华州、马里兰州、新泽西州、北卡罗来纳州、南卡罗来纳州和弗吉尼亚州报告了宋内志贺菌感染疫情。在此期间，观察到全州志贺菌病发病率增加了5至40倍。这些增加主要归因于多个日托场所的疫情持续时间延长并蔓延至整个社区。通过脉冲场凝胶电泳（PFGE）分析，来自这些州以及纽约市和费城的宋内志贺菌分离株在基因上相似。许多这些分离株缺乏发酵鼠李糖的能力，这在宋内志贺菌中并不常见。本报告总结了这些疫情，并描述了将它们联系起来的实验室特征。这些发现强调了对孤立的志贺菌病疫情做出快速和协调的公共卫生应对措施的重要性。
