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[载脂蛋白A和B以及其余脂质组分作为老年人蛋白质 - 热量营养不良指标的意义]

[Significance of apolipoproteins A and B and the remaining lipid fractions as indicators of protein-calorie malnutrition in the elderly].

作者信息

Santi Cano M J, Barba Chacón A, Mangas Rojas A, García Rojas J F, Millán Núñez-Cortés J, Zamora Madaria E

机构信息

Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz.

出版信息

Rev Clin Esp. 1992 Oct;191(5):252-5.

PMID:1475439
Abstract

Effects of calorie/protein malnourishment have been studied on plasma concentrations of cholesterol, triglycerides, HDL-C, LDL-C and apolipoproteins A and B, in institutionalized elderly people, 53 males and 62 females, of whom 19 females and 12 males were malnourished. In malnourished patients, total cholesterol and LDL-C were significantly lower both in males and in females, but HDL-C was lower only in females. No significant differences in plasma triglycerides were found between the control and the malnourished groups. Apolipoprotein A showed no significant changes on malnourished males, but did show a significant lowering in malnourished females. On the opposite, apolipoprotein B was lower in males than in females. The lowering in cholesterol in malnourished patients leads us to think that this could be a early predictor of nutritional risk in the elderly.

摘要

针对53名男性和62名女性的机构养老老年人(其中19名女性和12名男性存在营养不良),研究了热量/蛋白质营养不良对血浆胆固醇、甘油三酯、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)以及载脂蛋白A和B浓度的影响。在营养不良的患者中,男性和女性的总胆固醇和低密度脂蛋白胆固醇均显著降低,但高密度脂蛋白胆固醇仅在女性中降低。对照组和营养不良组之间的血浆甘油三酯未发现显著差异。载脂蛋白A在营养不良的男性中无显著变化,但在营养不良的女性中确实显著降低。相反,载脂蛋白B在男性中低于女性。营养不良患者胆固醇的降低使我们认为这可能是老年人营养风险的早期预测指标。

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