Gorman L L, O'Hara M W, Figueiredo B, Hayes S, Jacquemain F, Kammerer M H, Klier C M, Rosi S, Seneviratne G, Sutter-Dallay A-L
Iowa Depression and Clinical Research Center, University of Iowa, Iowa City 52242, USA.
Br J Psychiatry Suppl. 2004 Feb;46:s17-23. doi: 10.1192/bjp.184.46.s17.
To date, no study has used standardised diagnostic assessment procedures to determine whether rates of perinatal depression vary across cultures.
To adapt the Structured Clinical Interview for DSM-IV Disorders (SCID) for assessing depression and other non-psychotic psychiatric illness perinatally and to pilot the instrument in different centres and cultures.
Assessments using the adapted SCID and the Edinburgh Postnatal Depression Scale were conducted during the third trimester of pregnancy and at 6 months postpartum with 296 women from ten sites in eight countries. Point prevalence rates during pregnancy and the postnatal period and adjusted 6-month period prevalence rates were computed for caseness, depression and major depression.
The third trimester and 6-month point prevalence rates for perinatal depression were 6.9% and 8.0%, respectively. Postnatal 6-month period prevalence rates for perinatal depression ranged from 2.1% to 31.6% across centres and there were significant differences in these rates between centres.
Study findings suggest that the SCID was successfully adapted for this context. Further research on determinants of differences in prevalence of depression across cultures is needed.
迄今为止,尚无研究采用标准化诊断评估程序来确定围产期抑郁症的发病率是否因文化而异。
对《精神疾病诊断与统计手册第四版》(DSM-IV)障碍的结构化临床访谈(SCID)进行改编,以评估围产期的抑郁症及其他非精神病性精神疾病,并在不同中心和文化中试用该工具。
对来自八个国家十个地点的296名妇女在妊娠晚期和产后6个月使用改编后的SCID和爱丁堡产后抑郁量表进行评估。计算妊娠期间和产后的时点患病率以及调整后的6个月期间患病率,以确定病例、抑郁症和重度抑郁症的情况。
围产期抑郁症的妊娠晚期和6个月时点患病率分别为6.9%和8.0%。各中心产后6个月围产期抑郁症的期间患病率在2.1%至31.6%之间,各中心之间的这些患病率存在显著差异。
研究结果表明,SCID已成功适用于此背景。需要进一步研究不同文化中抑郁症患病率差异的决定因素。