Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, Du Cane Road, London, W12 ONN, UK.
Arch Womens Ment Health. 2009 Jun;12(3):135-41. doi: 10.1007/s00737-009-0062-9. Epub 2009 Apr 1.
Pregnancy and the postpartum may affect symptoms of depression. However it has not yet been tested how the symptoms used for the DSM IV diagnosis of depression discriminate depressed from non depressed women perinatally. A modified version of the Structured Clinical Interview for DSM IV (SCID interview) was used that allowed assessment of all associated DSM IV symptoms of depression with depressed and non depressed women in pregnancy and the postpartum period. Loss of appetite was not associated with depression either ante or postnatally. The antenatal symptom pattern was different from the postnatal. The sensitivity of the symptoms ranged from 0.7% to 51.6%, and specificity from 61.3% to 99.1%. The best discriminating symptoms were motor retardation/agitation and concentration antenatally, and motor retardation/agitation, concentration and fatigue postnatally. Depression in pregnancy and postpartum depression show significantly different symptom profiles. Appetite is not suitable for the diagnosis of depression in the perinatal period.
怀孕和产后可能会影响抑郁症状。然而，目前尚未研究用于 DSM-IV 抑郁诊断的症状如何区分围产期抑郁和非抑郁女性。使用了经过修改的 DSM-IV 结构临床访谈（SCID 访谈），该访谈允许评估怀孕期间和产后抑郁和非抑郁女性的所有相关 DSM-IV 抑郁症状。产前食欲减退与抑郁无关。产前症状模式与产后不同。症状的敏感性范围为 0.7%至 51.6%，特异性为 61.3%至 99.1%。最好的鉴别症状是产前的运动迟缓和激动以及注意力不集中，产后是运动迟缓和激动、注意力不集中和疲劳。妊娠和产后抑郁症的症状谱明显不同。食欲不适用于围产期的抑郁诊断。
