Faculty of Psychology, Universidade de Santiago de Compostela, Spain.
Faculty of Psychology, Universidade de Santiago de Compostela, Spain.
J Affect Disord. 2019 Mar 1;246:515-521. doi: 10.1016/j.jad.2018.12.075. Epub 2018 Dec 24.
The Edinburgh Postnatal Depression Scale (EPDS) is a self-reported scale designed to detect postnatal depression, and also has been validated in multiple countries for its use during pregnancy, but not in Spain. The objective of this study was to validate the EPDS as a screening instrument to detect depression during different trimesters of pregnancy in Spanish women.
Longitudinal study of a large, unselected sample of 569 pregnant women who were assessed in the first, second and third trimesters of pregnancy by using the EPDS and the Structured Clinical Interview for DSM-IV (SCID). We evaluated the area under the ROC curve (AUC), sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and overall accuracy (OA).
The optimal cut-off point score of the EPDS for screening current SCID diagnosis of combined depression was 9 or more in the first trimester of pregnancy (AUC of 0.76, sensitivity of 67.5%, specificity of 70.9%, PPV of 14.9%, NPV of 96.7%; and OA of 70.7%) and 10 or more in the second and third trimesters of pregnancy (AUC of 0.89 and 0.89, respectively; sensitivity of 81.5% and 78.1%, respectively; specificity of 86.0% and 81.9, respectively; PPV of 23.4% and 21.6%, respectively; NPV of 98.9% and 98.3, respectively; and OA 85.8% and 81.7%, respectively). Likewise, the optimal cut-off point score during pregnancy was 10 or more (AUC of 0.76, sensitivity of 72.4%, specificity of 79.3%, PPV of 18.2%, NPV of 97.8%, and OA of 78.9%).
This study is limited due to the low rate of depression cases.
EPDS is an adequate instrument for screening depression in Spanish pregnant women.
爱丁堡产后抑郁量表（EPDS）是一种自我报告量表，旨在检测产后抑郁症，并且已经在多个国家验证了其在怀孕期间的使用，但在西班牙尚未验证。本研究的目的是验证 EPDS 作为一种筛查工具，以检测西班牙孕妇在不同孕期的抑郁情况。
对 569 名未选择的孕妇进行了一项大型纵向研究，这些孕妇在怀孕的第一、二、三孕期分别使用 EPDS 和 DSM-IV 结构临床访谈（SCID）进行评估。我们评估了 ROC 曲线下面积（AUC）、敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和总准确率（OA）。
对于筛查当前 SCID 诊断的混合性抑郁，EPDS 的最佳截断点分数在孕早期为 9 分或以上（AUC 为 0.76，敏感性为 67.5%，特异性为 70.9%，PPV 为 14.9%，NPV 为 96.7%，OA 为 70.7%），在孕中期和孕晚期为 10 分或以上（AUC 分别为 0.89 和 0.89，敏感性分别为 81.5%和 78.1%，特异性分别为 86.0%和 81.9%，PPV 分别为 23.4%和 21.6%，NPV 分别为 98.9%和 98.3%，OA 分别为 85.8%和 81.7%）。同样，怀孕期间的最佳截断点分数为 10 分或以上（AUC 为 0.76，敏感性为 72.4%，特异性为 79.3%，PPV 为 18.2%，NPV 为 97.8%，OA 为 78.9%）。
本研究由于抑郁病例数量低而受到限制。
EPDS 是一种评估西班牙孕妇抑郁的有效工具。
