Simonoff Emily, Elander James, Holmshaw Janet, Pickles Andrew, Murray Robin, Rutter Michael
Department of Child and Adolescent Psychiatry, Guy's, King's and St Thomas' Medical School and Institute of Psychiatry, London, UK.
Br J Psychiatry. 2004 Feb;184:118-27. doi: 10.1192/bjp.184.2.118.
Antisocial behaviour in adult life has its roots in childhood.
To explore the independent and joint effects of childhood characteristics on the persistence of antisocial behaviour into adult life.
A clinical sample of twins who were systematically ascertained in childhood was followed up 10-25 years later. A total of 225 twins were interviewed regarding childhood and adult psychiatric disorder, psychosocial functioning, and psychosocial and cognitive risk factors.
In univariate analyses, childhood hyperactivity and conduct disorder showed equally strong prediction of antisocial personality disorder (ASPD) and criminality in early and mid-adult life. Lower IQ and reading problems were most prominent in their relationships with childhood and adolescent antisocial behaviour. In multivariate modelling childhood conduct disorder and hyperactivity predicted adult ASPD even when intervening risk factors were accounted for. The number of hyperactive and conduct symptoms also predicted adult outcome.
Childhood disruptive behaviour has powerful long-term effects on adult antisocial outcomes, which continue into middle adulthood. The importance of number of symptoms, the presence of disruptive disorder, and intermediate experiences highlight three areas where interventions might be targeted.
成年期的反社会行为源于童年时期。
探讨童年特征对反社会行为持续至成年期的独立及共同影响。
对童年时期经系统确定的双胞胎临床样本进行随访,随访时间为10至25年后。共对225对双胞胎进行了访谈,内容涉及童年和成人期精神疾病、心理社会功能以及心理社会和认知风险因素。
在单变量分析中,童年期多动和品行障碍对成年早期和中期的反社会人格障碍(ASPD)和犯罪行为具有同样强烈的预测作用。较低的智商和阅读问题在与童年及青少年反社会行为的关系中最为突出。在多变量模型中,即使考虑了中间风险因素,童年期品行障碍和多动仍可预测成人期的ASPD。多动和品行症状的数量也可预测成人期结局。
童年期破坏性行为对成人期反社会结局具有强大的长期影响,这种影响会持续至中年期。症状数量、破坏性行为障碍的存在以及中间经历的重要性突出了可能进行干预的三个领域。