Costea I, Diaconescu M R, Terinte R, Glod M, Chiriac R, Bulimar V
Facultatea de Medicină Stomatologică, Clinica a IV-a Chirurgie, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi.
Rev Med Chir Soc Med Nat Iasi. 2003 Jul-Sep;107(3):609-12.
The prophylactic use of antibiotics in the purpose of decreasing the frequency and severity of surgical infections is still controversial. The practical need of defining the concept of antibiotic prophylaxis gave rise to numerous polemics in the literature. This paper presents a retrospective study on 103 cases whom diagnostics were colon and rectum cancer, that were operated in the IV-th Surgical Clinic in 1993-2002 period; at these patients was done antibiotic prophylaxis local and systemic before, during and after operating. This method made possible the registration of a minimum number of cases with surgical infection (7 cases, representing only 7% of the operated patients): a case (1%) with peritoneal collection (needing the surgical evacuation of this collection) and in 6 cases, parietal superficial infections, which imposed the prolong of drainage for almost 7 days. Starting from the basic principles of antibiotic therapy, this paper aims at outlining practical guidelines for a judicious antibiotic prophylaxis.
为降低手术感染的发生率和严重程度而预防性使用抗生素仍存在争议。界定抗生素预防概念的实际需求引发了文献中的众多争论。本文对1993年至2002年期间在第四外科诊所接受手术的103例结肠癌和直肠癌患者进行了回顾性研究；这些患者在手术前、手术期间和手术后均进行了局部和全身抗生素预防。这种方法使得手术感染病例数最少（7例，仅占手术患者的7%）得以记录：1例（1%）发生腹腔积液（需要手术引流该积液），6例发生腹壁浅表感染，这些感染导致引流延长近7天。本文从抗生素治疗的基本原则出发，旨在概述明智的抗生素预防实用指南。
