Matsuo Tatsuhiro, Takeuchi Hiroyuki
Faculty of Agriculture, Kagawa University, Ikenobe, Kita-gun, Miki-cho, Kagawa 761-0795, Japan.
Br J Nutr. 2004 Feb;91(2):219-25. doi: 10.1079/BJN20031041.
The effects of structured medium- and long-chain triacylglycerols (MLCT) in diets containing 50-200 g fat/kg on body fat accumulation were compared with those of long-chain triacylglycerols (LCT) in rats. In rats fed ad libitum, weights of intra-abdominal adipose tissues and carcass fat contents were significantly smaller (P<0.05) in rats fed the 150-200 g MLCT/kg diet than in rats fed 150-200 g LCT/kg diet. Serum and liver triacylglycerol contents were significantly greater (P<0.05) in rats fed 200 g MLCT/kg diet, as were hepatic capacities of citrate synthase and cytochrome oxidase (P<0.05). The effects of MLCT on body fat were also examined in adult rats fed a limited amount of food (approximately 50 % of ad libitum intake). Reduction of body fat deposition during the food restriction was the same between in LCT and MLCT groups. These results suggest that accumulation of body fat was less efficient during long-term feeding of MLCT than LCT in rats fed high-fat diets ad libitum. The effect of MLCT on body fat might be influenced by the dietary fat content or by energy sufficiency.
将含50 - 200 g脂肪/千克的日粮中结构化中长链甘油三酯（MLCT）对大鼠体脂积累的影响与长链甘油三酯（LCT）进行了比较。在自由采食的大鼠中，饲喂150 - 200 g MLCT/千克日粮的大鼠腹腔内脂肪组织重量和胴体脂肪含量显著低于（P<0.05）饲喂150 - 200 g LCT/千克日粮的大鼠。饲喂200 g MLCT/千克日粮的大鼠血清和肝脏甘油三酯含量显著更高（P<0.05），柠檬酸合酶和细胞色素氧化酶的肝脏活性也是如此（P<0.05）。还在限食（约自由采食量的50%）的成年大鼠中研究了MLCT对体脂的影响。在食物限制期间，LCT组和MLCT组体脂沉积的减少情况相同。这些结果表明，在自由采食高脂日粮的大鼠中，长期饲喂MLCT时体脂积累的效率低于LCT。MLCT对体脂的影响可能受日粮脂肪含量或能量充足程度的影响。
