Avellón Ana, Trallero Gloria, Merino Begoña, Pachón Isabel, Sanz Carmen, Pérez-Breña Pilar
Laboratorio Nacional de Poliovirus, Servicio de Virología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, España.
Enferm Infecc Microbiol Clin. 2004 Feb;22(2):77-82. doi: 10.1016/s0213-005x(04)73038-4.
An initiative to achieve global eradication of poliomyelitis was proposed in 1988. Since then, World Health Organization (WHO) efforts have been focused on reaching and maintaining high vaccination coverage and on implementing effective surveillance systems. Additionally, since 1998 the WHO has urged health authorities from countries over the world to locate and control the wild polioviruses stored in laboratories as well as potentially infectious materials that could contain these viruses or originate them under particular circumstances.
In Spain the Wild Poliovirus Containment Plan was initiated in 1999. All Spanish laboratories were inventoried and a specially designed questionnaire was distributed to them. The responses were analyzed.
A total of 3209 laboratories were surveyed and 10 of them were found to contain infectious or potentially infectious material with wild poliovirus. The heads of these laboratories were informed about the Containment Plan and were requested to destroy this material under proper conditions. The laboratories that did not destroy the viruses adopted the BSL2/polio bio-safety measures.
Despite its complexity, the search process was completed within the schedule established by the WHO, thanks to the efforts of health authorities from the Autonomous Communities. Spain reported its results to the WHO Regional Commission for the Certification of Poliomyelitis Eradication in May 2002.
1988年提出了在全球根除脊髓灰质炎的倡议。自那时以来,世界卫生组织(WHO)的工作重点一直是实现并维持高疫苗接种率以及实施有效的监测系统。此外,自1998年以来,WHO敦促世界各国的卫生当局查找并控制储存在实验室的野生脊髓灰质炎病毒以及在特定情况下可能含有这些病毒或产生这些病毒的潜在感染性材料。
西班牙于1999年启动了野生脊髓灰质炎病毒控制计划。对西班牙所有实验室进行了清查,并向它们发放了一份专门设计的调查问卷。对调查结果进行了分析。
共调查了3209个实验室,发现其中10个实验室含有带有野生脊髓灰质炎病毒的感染性或潜在感染性材料。已将控制计划告知这些实验室的负责人,并要求他们在适当条件下销毁这些材料。未销毁病毒的实验室采取了二级生物安全防护实验室/脊髓灰质炎生物安全措施。
尽管搜索过程复杂,但由于自治区卫生当局的努力,搜索工作在WHO规定的时间内完成。西班牙于2002年5月向WHO脊髓灰质炎根除认证区域委员会报告了其结果。